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Chemical Composition


TOPVEIN contains the traditional superior blend of the Mayeyanin Formula.


A lectin, steroidal saponins, asparaginase, sapogenins - Sarsasapogenin, Protodioscin, diosgenin, Vitamins, and Minerals.


Lectin, an active ingredient contained in phaseolus vulgaris with a unique hemagglutinating activity is an anti HIV protein present in each TOPVEIN capsule.

Other active plant ingredients carrying medicinal importance in Topvein are steroidal saponins, asparaginase, and sapogenins which include sarsasapogenin, protodioscin, and diosgenin.


Vitamin K69.6%, vitamin A20.2%, folate17.4% , iron15.9% , vitamin B112.6%, vitamin C12.5%, copper12.5%, tryptophan12.5%, vitamin B211.1%, fiber10.9%, manganese10.5%, molybdenum8.9%, potassium7.7%, vitamin E7.5%, phosphorus6.9%, vitamin B36.5%, vitamin B66%, protein5.9%,  choline5%, zinc4.8%, magnesium4.6%, selenium4.4%, Vitamin B53.7%, calcium3.2%, Calories (26)1%.



A lectin or Phytohaemagglutinin or (PHA) with a unique hemagglutinating activity was isolated from phaseolus vulgaris during a study. This protein exhibited mitogenic activity on murine splenocytes. The viability of hepatoma (HepG2), leukemia (L1210), and leukemia (M1) cells was reduced in the presence of lectin, which also exerted an inhibitory activity toward HIV-1 reverse transcriptase IC(50) of 73 microM. Thus lectin is an active protein which inhibits HIV-1.


Food saponins have been used in complimentary and traditional medicine against a variety of diseases including several cancers. Diosgenin, a naturally occurring steroid saponin found abundantly in legumes and yams, is a well-known precursor of various synthetic steroidal drugs that are extensively used in the pharmaceutical industry. Over the past decade, a series of preclinical and mechanistic studies have been conducted to understand the role of diosgenin as a chemopreventive/therapeutic agent against several cancers. Through studies, the anticancer mode of action of diosgenin has been demonstrated via modulation of multiple cell signalling events involving critical molecular candidates associated with growth, differentiation, apoptosis, and oncogenesis. Altogether, these preclinical and mechanistic findings strongly implicate the use of diosgenin as a novel, multitarget-based chemopreventive or therapeutic agent against several cancer types.


Asparaginase in medicine and many medical products is used for the treatment of malignant tumors of lymphocytes and, in particular, is widely used for acute leukemia. Moreover, in the treatment of cancer cells, high amounts of L-asparagine are required when the malignant tumors grow, and thus L-asparaginase is used to degrade L-asparagine so as to inhibit the growth of malignant tumors, thus reducing or eliminating tumor cells.


Sarsasapogenin and its C-25 epimersmilagenin lowered blood sugar and reversed diabetic weight gain in experiments within mice with a mutant diabetes gene (db). Both steroids also halted the decline in muscarinic acetylcholine receptors (mAChRs) in animal models of Alzheimer's disease. In both cases, the effects seem to be specific to the 5β-configuration, the cis-linkage between rings A and B, as diosgenin(with a Δ5 double bond which can be hydrogenated in the body) had much lower anti-diabetic activity (and no significant effect on mAChRs while tigogenin (the 5α-epimer of smilagenin) showed no effect at all in either study.


Extracts fromTribulusterrestrisstandardised for protodioscin content have been demonstrated to produce proerectile effects in isolated tissues and aphrodisiac action in several animal species. It is thought protodioscin achieves this primarily through causing an increase in androgen receptor immunoreacivity, meaning it increases the concentration of androgen receptors in cells, causing the organism to become more sensitive to androgens like testosterone and DHT. Based on the results of a conducted study, it is now concluded that:
1. Treating diabetic men with Tribulusterrestris extract resulted in a better sense of well-being and sexual responses as compared to those treated with placebo.

2. Treatment with Tribulus extract was successful in reducing the fasting blood sugar levels, and may be a viable option in reducing glucotoxicity impact on blood vessels and nervous system in diabetic subjects.


Topvein in capsule form with lectin as an active protein (molecule) which is an Ant proliferative with HIV-1 Reverse Transcriptive Inhibitory Activity may be used initially as a complimentary medicine in the management of immune-suppression to avoid the consequent opportunist infections and diseases found in AIDS Related Complexes (ARC).

Other active proteins which include - Asparanin A, Sarsasapogenin, Protodioscin, and diosgenin contained in Topvein are a combination of vital inflammatory phytonutrients; with a wide variety of antioxidant nutrients, including vitamin C, beta-carotene, Vitamin E, and the mineral Zinc, manganese, and selenium.

Topvein contains phosphate and vitamin B, which gives it rematerializing and stimulating properties. Also, Topvein has rare nutrients: copper, iron, zinc, manganese, chrome, calcium, sodium, potassium, which gives it depurative and laxative properties and making it a hepatic and renal drainer.

Topvein may also be used to control some stomach infections, clean the liver, lungs, and intestines off their wastes and toxins. Apart from its depurative effects, the herbal formula also has a protecting action on the arteries and may prevent the development of arteriosclerosis and clean the blood.

Topvein may also be used to treat physical or intellectual asthenia, anaemia, and convalescence, and cardio-vascular erythrism. Taking Topvein stimulates the decrease of glycosuria and increase diuresis, a reason why it is recommended for diabetics.

Topvein has the properties of eliminating toxins from the digestive system and it is the more reason Topvein is highly valued for its use in stimulating and strengthening kidney functioning.

Vitamin A

Every cell in your body needs vitamin A. This nutrient regulates the growth and division of your cells and it helps your body produce white blood cells when you need to fight an illness or infection. It plays a role in remodelling bone and it keeps the cells that line your body's interior surfaces healthy. Smokers should avoid high-dose supplements of beta-carotene, according to Harvard School of Public Health, because it may increase their risk of lung cancer, but getting the recommended amount through food is healthy and safe.

Vitamin A also plays an essential role in maintaining healthy white blood cells by protecting mucosal cells, your body's first line of defence against sickness and infection. Vitamin A also builds T-lymphocyte white blood cells that help protect your body from bacterial or viral infection. Because of the high concentrations of these vitamins naturally occurring in even small amounts of Topvein, taking Topvein as directed is one of the most important things you can do to keep your immune system at its full strength.

Vitamin E

Vitamin E is a fat-soluble antioxidant that protects your cell membranes from damage and may prevent LDL cholesterol from oxidizing and forming plaque in your arteries. Women who are at risk for deep vein thrombosis may benefit from getting an adequate amount of vitamin E because it may prevent DVT from developing. Some research indicates that vitamin E might help prevent some types of cancer. A study published in the "Journal of the National Cancer Institute" in 2012 noted that middle-aged or older Chinese people who took high amounts of vitamin E, either from diet or supplements had a lower incidence of liver cancer than those who did not.

Vitamin C

Scientists have determined that your body needs vitamin C to produce collagen, cartilage, tendons, ligaments and the basic protein in your bones. Vitamin C also functions as an antioxidant, protecting you from the damage done by free radicals.
Thus, a healthy dose of vitamin C is essential to the proper functioning of your immune system. Vitamin C protects white blood cells when they are attacked by free radicals, viral or bacterial infection.

B Vitamins

The B-complex group of vitamins includes vitamins B-6 and B-12, as well as thiamin, riboflavin, niacin, folate, biotin and pantothenic acid. These vitamins work together to help your body metabolize the carbohydrates, protein and fat that you eat. They also function as antioxidants, protecting you from illness and premature aging. The IOM recommends men get 1 milligram of thiamin, 12 milligrams of niacin and 1.1 milligrams of riboflavin per day and that women get .9 milligrams of thiamin, 11 milligrams of niacin and .9 milligrams of riboflavin. Men and women both need 30 micrograms of biotin, 320 micrograms of folate and 6 milligrams of pantothenic acid per day.


Zinc actually does help you fight off a cold, according to HarriHemilä, a researcher at the University of Helsinki in Finland. In 2011, Hemilä published a study in the "Open Respiratory Medical Journal" in which he found that people who had colds and took doses of more than 75 milligrams of zinc experienced a shorter duration of their colds, while people who took less than 75 milligrams per day had colds that lasted longer. According to James P. McClung, Ph.D., who published an article on zinc in "Military Medicine," a publication of the U.S. Army Research Institute of Environmental Medicine, zinc supplementation can help treat and prevent diarrhea, pneumonia, malaria and other dangerous conditions that befall soldiers, so he recommends all military personnel get adequate amounts of zinc in their diets.

Your body requires essential minerals and vitamins for every process and function. These nutrients work in symphony to grow, heal, repair and maintain your body's cells, organs, systems and skeleton. Vitamins and minerals are needed in varying amounts and some form key parts of structures such as red blood cells and bones. Deficiencies of minerals and vitamins can lead to fatigue, illness and disease. A balanced daily diet generally provides the essential nutrients your body needs to stay healthy; a doctor can determine if you require vitamin or mineral supplements to enhance your regular nutrition.


Metabolism burns ingested and stored food nutrients to produce energy that your body can use, through a number of complex processes. Vitamins and minerals play a key role in digestion and metabolism. The University of Maryland Medical Center notes that vitamin B2 or riboflavin is essential to form a coenzyme, which combines oxygen to cellular mechanisms that produce energy. All the B vitamins, including vitamins B6 and B12, are important for the metabolism of carbohydrates, proteins and fats. Minerals such as magnesium are also important in energy metabolism. Foods high in B vitamins and magnesium include spinach, broccoli, beans, oats, fish, poultry and eggs.

Heart Health

Essential vitamins from your daily nutrition are also needed to prevent heart disease. Nutrients such as vitamins A, C, and E as well as beta carotene have antioxidant properties that help reduce inflammation, which may reduce the risk of heart disease. A diet high in fruits and vegetables is rich in these vitamins and other nutrients. The University of Maryland Medical Centre also notes that vitamin B3 or niacin is used for lowering unhealthy cholesterol levels to improve cardiovascular health. However, high doses of this vitamin are needed and should only be taken under the supervision of your doctor.

Bone Health

Minerals and vitamins are vital for maintaining bone health and preventing bone diseases such as osteoporosis or brittle and weakened bones. The hard matrix of bones is composed of minerals such as calcium, magnesium and phosphorus. Research published in the "British Journal of Nutrition" notes that vitamin D is needed to help your body absorb calcium from food and supplementing these two nutrients may help prevent bone loss and reduce the risk of fractures. Vitamin K also plays a role in bone health to support the role of vitamin D and calcium.


Reproductive health and fertility depend on the function of a number of organs, structures and hormones, as well as cell production. Minerals and vitamins are needed to help grow, repair and maintain these intricate systems and processes in both men and women. The mineral zinc is important for fertility health in men and improves sperm count and mobility. Zinc-rich foods include red meat, poultry, beans, nuts, pumpkin seeds and oysters. lists a number of vitamins and minerals that are also needed for reproductive health including vitamin C, E and B12, beta carotene, folic acid and selenium, and renal drainer.